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SPARCL2006
Atorvastatin 80 mg after non-cardioembolic stroke/TIA reduces recurrent stroke; hemorrhagic-stroke signal HR 1.66.
OPTIMAS2024
Early DOAC (≤4 d) noninferior to delayed start after AF-related stroke in the largest trial to date.
ANNEXA-42019
Single-arm cohort: andexanet reduced anti-FXa by 92% with 82% hemostatic efficacy in FXa-inhibitor major bleeding.
ENRICH2024
Minimally invasive parafascicular surgery for lobar ICH 30–80 mL improves utility-weighted mRS at 180 d.
INSPIRES2024
Late-window DAPT (24–72 h) after atherosclerotic minor stroke/TIA cuts recurrent stroke.