Clinical Question
Does mobile stroke unit dispatch improve outcomes?
Synthesises 4 trialspatient-level functional outcomes from prehospital MSU programs and adjacent prehospital intervention trials
What does the guideline say?
- §2.5 Mobile Stroke Units· 2026
For patients with AIS who are eligible for IVT, treatment with IVT on a mobile stroke unit (MSU) should be used because it improves functional outcomes compared with standard EMS transport (COR 1, LOE B-R). In endovascular thrombectomy-eligible patients, MSU dispatch may help triage patients to the appropriate thrombectomy-capable center (COR 2a, LOE B-R).
The trials cited in the guideline's supportive text appear below.
Trials in this question· 4
RIGHT-22019
No benefitOR 1.25
Ultra-acute transdermal GTN for presumed stroke shows no benefit and a harm signal in ICH.
No benefitOR 1.25
B_PROUD2021
cOR 0.71cOR 0.71 (less mRS)
MSU dispatch in urban EMS shifts ordinal mRS toward less disability vs conventional ambulance.
cOR 0.71cOR 0.71 (less mRS)
BEST-MSU2021
NNT 13uw-mRS OR 2.14
Prehospital MSU care saves 36 min and improves outcomes in tPA-eligible stroke.
NNT 13uw-mRS OR 2.14
INTERACT42024
NeutralOR 1.00
Prehospital BP lowering in undifferentiated stroke helps hemorrhagic and hurts ischemic patients (net null).
NeutralOR 1.00
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